Changes in glutathione S-transferase activity in DDT resistant natural Mexican populations of Anopheles albimanus under different insecticide resistance management strategies

R. Patricia Penilla, Américo D. Rodríguez, Janet Hemingway, José L. Torres, Francisco Solis, Mario H. Rodríguez

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)

Abstract

Biochemical assays on Anopheles albimanus collected for 3 years in southern Mexico villages after house spraying of a single insecticide [DDT or a pyrethroid (PYR)], a two insecticide mosaic [organophosphate (OP)/PYR] or a three insecticide annual rotation (OP-PYR-carbamate), defined he relative rates of selection of glutathione S-transferase-based resistance. After 3 years of rotation, mosaic and single PYR strategies, there was a decrease in the glutathione S-transferase (GST) activity, returning to susceptible levels, with few variations. In the rotation strategy, GST activity increased significantly in one group of villages, when OP treatment was replaced by the PYR in the 2nd treatment year. While, GST activity increased only in one village out of six continuously PYR-treated in the 1st year. In the DDT-treated villages, one group had increased activity in the 1 st year, but this declined in years 2 and 3; GST activity of the other DDT-treated group were unchanged during the trial. (c) 2006 Elsevier Inc. All rights reserved.

Original languageEnglish
Pages (from-to)63-71
Number of pages9
JournalPesticide Biochemistry and Physiology
Volume86
Issue number2
DOIs
Publication statusPublished - 1 Oct 2006

Keywords

  • Anopheles albimanus
  • Glutathione S-transferase
  • Insecticide selection pressures
  • Mexico
  • Mosaic
  • Resistance management strategies
  • Rotation
  • Vector control

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