Abstract
Antimicrobial resistance genes (ARGs) are often associated with mobile genetic elements (MGEs), which facilitate their movement within and between bacterial populations. Detection of mobility is therefore important to understand the dynamics of MGE dissemination and their associated genes, especially in resistant clinical isolates that often have multiple ARGs associated with MGEs. Therefore, this study aimed to develop an entrapment vector to capture active MGEs and ARGs in clinical isolates of Escherichia coli.
| Original language | English |
|---|---|
| Pages (from-to) | 832-842 |
| Number of pages | 11 |
| Journal | Journal of Applied Microbiology |
| Volume | 130 |
| Issue number | 3 |
| Early online date | 2 Sept 2020 |
| DOIs | |
| Publication status | Published - 1 Mar 2021 |
Keywords
- antimicrobial resistance
- clinical isolates
- entrapment vector
- insertion sequence
- mobile genetic element
- translocatable unit
- trimethoprim resistance