Bleach-digested sputum smears for the diagnosis of TB in HIV-infected individuals

S. Douthwaite; M. A. Yassin; Bertie Squire; I. Arbide; Luis Cuevas

doi:10.1258/004947507779952014

Bleach-digested sputum smears for the diagnosis of TB in HIV-infected individuals

S. Douthwaite, M. A. Yassin, Bertie Squire, I. Arbide, Luis Cuevas

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

We describe the performance of bleach-digested Zeihl-Neelsen (ZN) smears in TB suspects with/without HIV. In total, 51 (26%) and 62 (31%) out of the first 198 spot and digested smears were positive. Seven of the 30 HIV-positive patients had TB and their ZN smears were negative, scanty or 1+. Six of seven digested smears were scanty. Forty-two of 115 HIV-negative patients had TB. Eleven (26%) of their digested smears were negative, 12 (29%) scanty and 19 (45%) positive. Despite the lower bacilli numbers of HIV-positive patients, the technique had sensitivity and specificity similar to that in HIV-negative patients.

Original language	English
Pages (from-to)	35-36
Number of pages	2
Journal	Tropical Doctor
Volume	37
Issue number	1
DOIs	https://doi.org/10.1258/004947507779952014
Publication status	Published - 1 Jan 2007

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title = "Bleach-digested sputum smears for the diagnosis of TB in HIV-infected individuals",

abstract = "We describe the performance of bleach-digested Zeihl-Neelsen (ZN) smears in TB suspects with/without HIV. In total, 51 (26\%) and 62 (31\%) out of the first 198 spot and digested smears were positive. Seven of the 30 HIV-positive patients had TB and their ZN smears were negative, scanty or 1+. Six of seven digested smears were scanty. Forty-two of 115 HIV-negative patients had TB. Eleven (26\%) of their digested smears were negative, 12 (29\%) scanty and 19 (45\%) positive. Despite the lower bacilli numbers of HIV-positive patients, the technique had sensitivity and specificity similar to that in HIV-negative patients.",

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AU - Cuevas, Luis

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AB - We describe the performance of bleach-digested Zeihl-Neelsen (ZN) smears in TB suspects with/without HIV. In total, 51 (26%) and 62 (31%) out of the first 198 spot and digested smears were positive. Seven of the 30 HIV-positive patients had TB and their ZN smears were negative, scanty or 1+. Six of seven digested smears were scanty. Forty-two of 115 HIV-negative patients had TB. Eleven (26%) of their digested smears were negative, 12 (29%) scanty and 19 (45%) positive. Despite the lower bacilli numbers of HIV-positive patients, the technique had sensitivity and specificity similar to that in HIV-negative patients.

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Bleach-digested sputum smears for the diagnosis of TB in HIV-infected individuals

Abstract

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