Biochemical characterisation and substrate-specific proteolytic diversity of venom metalloproteinases in African puff adders

Mark Wilkinson; Cassie Modahl; David Waterhouse; Anthony J. Saviola; Laura-Oana Albulescu; Frank-Leonel Tianyi; Taline Kazandjian; Wolfgang Wüster; Francois Theart; George Oluoch; Robert Harrison; Nick Casewell

doi:10.1016/j.toxcx.2026.100253

Biochemical characterisation and substrate-specific proteolytic diversity of venom metalloproteinases in African puff adders

Mark Wilkinson
, Cassie Modahl
, David Waterhouse
, Anthony J. Saviola
, Laura-Oana Albulescu
, Frank-Leonel Tianyi
, Taline Kazandjian
, Wolfgang Wüster
, Francois Theart
, George Oluoch
, Robert Harrison
, Nick Casewell

University of Colorado
Institute of Primate Research
Bangor University
University of Namibia

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	100253
Journal	Toxicon: X
Volume	30
Early online date	16 Mar 2026
DOIs	https://doi.org/10.1016/j.toxcx.2026.100253
Publication status	E-pub ahead of print - 16 Mar 2026

Keywords

Angiotensin
Laminin
Pathology of envenoming
Puff adder
Toxins

Access to Document

10.1016/j.toxcx.2026.100253Licence: CC BY-NC-ND

1-s2.0-S2590171026000123-mainFinal published version, 6.97 MBLicence: CC BY-NC-ND

Cite this

Wilkinson, M., Modahl, C., Waterhouse, D., Saviola, A. J., Albulescu, L.-O., Tianyi, F.-L., Kazandjian, T., Wüster, W., Theart, F., Oluoch, G., Harrison, R., & Casewell, N. (2026). Biochemical characterisation and substrate-specific proteolytic diversity of venom metalloproteinases in African puff adders. Toxicon: X, 30, Article 100253. Advance online publication. https://doi.org/10.1016/j.toxcx.2026.100253

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author = "Mark Wilkinson and Cassie Modahl and David Waterhouse and Saviola, \{Anthony J.\} and Laura-Oana Albulescu and Frank-Leonel Tianyi and Taline Kazandjian and Wolfgang W{\"u}ster and Francois Theart and George Oluoch and Robert Harrison and Nick Casewell",

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doi = "10.1016/j.toxcx.2026.100253",

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T1 - Biochemical characterisation and substrate-specific proteolytic diversity of venom metalloproteinases in African puff adders

AU - Wilkinson, Mark

AU - Modahl, Cassie

AU - Waterhouse, David

AU - Saviola, Anthony J.

AU - Albulescu, Laura-Oana

AU - Tianyi, Frank-Leonel

AU - Kazandjian, Taline

AU - Wüster, Wolfgang

AU - Theart, Francois

AU - Oluoch, George

AU - Harrison, Robert

AU - Casewell, Nick

PY - 2026/3/16

Y1 - 2026/3/16

KW - Angiotensin

KW - Laminin

KW - Pathology of envenoming

KW - Puff adder

KW - Toxins

U2 - 10.1016/j.toxcx.2026.100253

DO - 10.1016/j.toxcx.2026.100253

M3 - Article

SN - 2590-1710

VL - 30

JO - Toxicon: X

JF - Toxicon: X

M1 - 100253

ER -