Biguanide-atovaquone synergy against Plasmodium falciparum in vitro

K. Jones, Steve Ward

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

The synergistic potential of a range of biguanides, their triazine metabolites, tetracyclines, and pyrimethamine in combination with atovaquone has been assessed. All five biguanides tested interacted synergistically with atovaquone against Plasmodium falciparum in vitro. All of the other compounds tested were either additive or antagonistic.

Original languageEnglish
Pages (from-to)2700-2703
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume46
Issue number8
DOIs
Publication statusPublished - 1 Aug 2002

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