Association between night blindness history and risk of diabetes in the Chinese population: a multi-center, cross sectional study

Jinbang Wang; Yunting Zhou; Yu Liu; Miaomiao Sang; Yuzhi Ding; Tingting Li; Xiaohang Wang; Vladmir Carvalho; Chengming Ni; Qianqian Wang; Zhensheng Cai; Huan Wang; Yang Chen; Zhanjia Shang; Duolao Wang; Shanhu Qiu; Zilin Sun

doi:10.1186/s12902-024-01721-2

Association between night blindness history and risk of diabetes in the Chinese population: a multi-center, cross sectional study

Jinbang Wang, Yunting Zhou, Yu Liu, Miaomiao Sang, Yuzhi Ding, Tingting Li, Xiaohang Wang, Vladmir Carvalho, Chengming Ni, Qianqian Wang, Zhensheng Cai, Huan Wang, Yang Chen, Zhanjia Shang, Duolao Wang, Shanhu Qiu, Zilin Sun

Clinical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Aims

Night blindness (NB), an important manifestation of VA deficiency, may be associated with the odds of diabetes. The aim of this study was to explore the probable association between NB history and diabetes in Chinese community-dwelling adults.

Methods

This multi-center, cross-sectional study enrolled a total of 5664 participants aged 18–82 years from eight sites in China. Information on demographics and medical history was collected using a standardized questionnaire. Diabetes was diagnosed based on the oral glucose tolerance test or a self-reported history. NB history was ascertained by a face-to-face interview with reference to the recommendation by the World Health Organization. Logistic regression analysis was used to evaluate the association between NB history and the odds of diabetes.

Results

A total of 5049 participants were finally included, with 252 ascertained with NB history and 1076 with diabetes. The mean age of included participants was 52.9 years, and the percentage of participants with NB history was significantly higher in participants with diabetes than those without (7.0% vs. 4.5%). The multivariable adjusted odds ratio for diabetes was 1.41 (95% confidence interval 1.06, 1.89) in participants with NB history compared with those without. Furthermore, mediation analysis showed that obesity, as assessed by waist-height ratio, partially mediated the relationship between NB history and increased odds of diabetes.

Conclusions

The results suggest that NB history might be associated with increased odds of diabetes in Chinese community-dwelling adults.

Original language	English
Article number	231
Pages (from-to)	e231
Journal	BMC Endocrine Disorders
Volume	24
Issue number	1
Early online date	29 Oct 2024
DOIs	https://doi.org/10.1186/s12902-024-01721-2
Publication status	Published - 29 Oct 2024

Keywords

Diabetes mellitus
Night blindness
Risk
Waist-height ratio

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1186/s12902-024-01721-2Licence: CC BY-NC-ND

12902 2024 Article 1721Final published version, 1.16 MBLicence: CC BY-NC-ND

Cite this

Wang, J., Zhou, Y., Liu, Y., Sang, M., Ding, Y., Li, T., Wang, X., Carvalho, V., Ni, C., Wang, Q., Cai, Z., Wang, H., Chen, Y., Shang, Z., Wang, D., Qiu, S., & Sun, Z. (2024). Association between night blindness history and risk of diabetes in the Chinese population: a multi-center, cross sectional study. BMC Endocrine Disorders, 24(1), e231. Article 231. https://doi.org/10.1186/s12902-024-01721-2

@article{51bc428bac344094ae5e0d995694fe2c,

title = "Association between night blindness history and risk of diabetes in the Chinese population: a multi-center, cross sectional study",

abstract = "AimsNight blindness (NB), an important manifestation of VA deficiency, may be associated with the odds of diabetes. The aim of this study was to explore the probable association between NB history and diabetes in Chinese community-dwelling adults.MethodsThis multi-center, cross-sectional study enrolled a total of 5664 participants aged 18–82 years from eight sites in China. Information on demographics and medical history was collected using a standardized questionnaire. Diabetes was diagnosed based on the oral glucose tolerance test or a self-reported history. NB history was ascertained by a face-to-face interview with reference to the recommendation by the World Health Organization. Logistic regression analysis was used to evaluate the association between NB history and the odds of diabetes.ResultsA total of 5049 participants were finally included, with 252 ascertained with NB history and 1076 with diabetes. The mean age of included participants was 52.9 years, and the percentage of participants with NB history was significantly higher in participants with diabetes than those without (7.0\% vs. 4.5\%). The multivariable adjusted odds ratio for diabetes was 1.41 (95\% confidence interval 1.06, 1.89) in participants with NB history compared with those without. Furthermore, mediation analysis showed that obesity, as assessed by waist-height ratio, partially mediated the relationship between NB history and increased odds of diabetes.ConclusionsThe results suggest that NB history might be associated with increased odds of diabetes in Chinese community-dwelling adults.",

keywords = "Diabetes mellitus, Night blindness, Risk, Waist-height ratio",

author = "Jinbang Wang and Yunting Zhou and Yu Liu and Miaomiao Sang and Yuzhi Ding and Tingting Li and Xiaohang Wang and Vladmir Carvalho and Chengming Ni and Qianqian Wang and Zhensheng Cai and Huan Wang and Yang Chen and Zhanjia Shang and Duolao Wang and Shanhu Qiu and Zilin Sun",

year = "2024",

month = oct,

day = "29",

doi = "10.1186/s12902-024-01721-2",

language = "English",

volume = "24",

pages = "e231",

journal = "BMC Endocrine Disorders",

issn = "1472-6823",

publisher = "BioMed Central Ltd",

number = "1",

}

Wang, J, Zhou, Y, Liu, Y, Sang, M, Ding, Y, Li, T, Wang, X, Carvalho, V, Ni, C, Wang, Q, Cai, Z, Wang, H, Chen, Y, Shang, Z, Wang, D, Qiu, S & Sun, Z 2024, 'Association between night blindness history and risk of diabetes in the Chinese population: a multi-center, cross sectional study', BMC Endocrine Disorders, vol. 24, no. 1, 231, pp. e231. https://doi.org/10.1186/s12902-024-01721-2

TY - JOUR

T1 - Association between night blindness history and risk of diabetes in the Chinese population: a multi-center, cross sectional study

AU - Wang, Jinbang

AU - Zhou, Yunting

AU - Liu, Yu

AU - Sang, Miaomiao

AU - Ding, Yuzhi

AU - Li, Tingting

AU - Wang, Xiaohang

AU - Carvalho, Vladmir

AU - Ni, Chengming

AU - Wang, Qianqian

AU - Cai, Zhensheng

AU - Wang, Huan

AU - Chen, Yang

AU - Shang, Zhanjia

AU - Wang, Duolao

AU - Qiu, Shanhu

AU - Sun, Zilin

PY - 2024/10/29

Y1 - 2024/10/29

N2 - AimsNight blindness (NB), an important manifestation of VA deficiency, may be associated with the odds of diabetes. The aim of this study was to explore the probable association between NB history and diabetes in Chinese community-dwelling adults.MethodsThis multi-center, cross-sectional study enrolled a total of 5664 participants aged 18–82 years from eight sites in China. Information on demographics and medical history was collected using a standardized questionnaire. Diabetes was diagnosed based on the oral glucose tolerance test or a self-reported history. NB history was ascertained by a face-to-face interview with reference to the recommendation by the World Health Organization. Logistic regression analysis was used to evaluate the association between NB history and the odds of diabetes.ResultsA total of 5049 participants were finally included, with 252 ascertained with NB history and 1076 with diabetes. The mean age of included participants was 52.9 years, and the percentage of participants with NB history was significantly higher in participants with diabetes than those without (7.0% vs. 4.5%). The multivariable adjusted odds ratio for diabetes was 1.41 (95% confidence interval 1.06, 1.89) in participants with NB history compared with those without. Furthermore, mediation analysis showed that obesity, as assessed by waist-height ratio, partially mediated the relationship between NB history and increased odds of diabetes.ConclusionsThe results suggest that NB history might be associated with increased odds of diabetes in Chinese community-dwelling adults.

AB - AimsNight blindness (NB), an important manifestation of VA deficiency, may be associated with the odds of diabetes. The aim of this study was to explore the probable association between NB history and diabetes in Chinese community-dwelling adults.MethodsThis multi-center, cross-sectional study enrolled a total of 5664 participants aged 18–82 years from eight sites in China. Information on demographics and medical history was collected using a standardized questionnaire. Diabetes was diagnosed based on the oral glucose tolerance test or a self-reported history. NB history was ascertained by a face-to-face interview with reference to the recommendation by the World Health Organization. Logistic regression analysis was used to evaluate the association between NB history and the odds of diabetes.ResultsA total of 5049 participants were finally included, with 252 ascertained with NB history and 1076 with diabetes. The mean age of included participants was 52.9 years, and the percentage of participants with NB history was significantly higher in participants with diabetes than those without (7.0% vs. 4.5%). The multivariable adjusted odds ratio for diabetes was 1.41 (95% confidence interval 1.06, 1.89) in participants with NB history compared with those without. Furthermore, mediation analysis showed that obesity, as assessed by waist-height ratio, partially mediated the relationship between NB history and increased odds of diabetes.ConclusionsThe results suggest that NB history might be associated with increased odds of diabetes in Chinese community-dwelling adults.

KW - Diabetes mellitus

KW - Night blindness

KW - Risk

KW - Waist-height ratio

U2 - 10.1186/s12902-024-01721-2

DO - 10.1186/s12902-024-01721-2

M3 - Article

SN - 1472-6823

VL - 24

SP - e231

JO - BMC Endocrine Disorders

JF - BMC Endocrine Disorders

IS - 1

M1 - 231

ER -

Association between night blindness history and risk of diabetes in the Chinese population: a multi-center, cross sectional study

Abstract

Keywords

UN SDGs

Access to Document

Fingerprint

Cite this