Assessment of the Hemophagocytic Lymphohistiocytosis HScore in Patients with Coronavirus Disease 2019

Kristina E.N. Clark, William Nevin, Tabitha Mahungu, Helen Lachmann, Animesh Singh

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

The clinical manifestation of moderate to severe coronavirus disease 2019 (COVID-19) has parallels to secondary hemophagocytic lymphohistiocytosis (HLH) both clinically and based on molecular inflammatory response. We found no evidence to support the utility of risk-stratifying COVID-19 patients using risk scoring methodology designed for HLH.
Original languageEnglish
Pages (from-to)E3110-E3112
JournalClinical Infectious Diseases
Volume73
Issue number9
DOIs
Publication statusPublished - 1 Nov 2021
Externally publishedYes

Keywords

  • COVID-19
  • cytokine storm
  • HLH
  • HScore

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