Antimalarial mannoxanes: hybrid antimalarial drugs with outstanding oral activity profiles and a potential dual mechanism of action.

James Chadwick; Richard K. Amewu; Francesc Marti; Fatima Bousejra El Garah; Raman Sharma; Neil G. Berry; Paul A. Stocks; Hollie Burrell-Saward; Sergio Wittlin; Matthias Rottmann; Reto Brun; Donatella Taramelli; Silvia Parapini; Steve Ward; Paul M. O'Neill

doi:10.1002/cmdc.201100196

Antimalarial mannoxanes: hybrid antimalarial drugs with outstanding oral activity profiles and a potential dual mechanism of action.

James Chadwick
, Richard K. Amewu
, Francesc Marti
, Fatima Bousejra El Garah
, Raman Sharma
, Neil G. Berry
, Paul A. Stocks
, Hollie Burrell-Saward
, Sergio Wittlin
, Matthias Rottmann
, Reto Brun
, Donatella Taramelli
, Silvia Parapini
, Steve Ward
, Paul M. O'Neill

Tropical Disease Biology

University of Liverpool
Liverpool School of Tropical Medicine
London School of Hygiene and Tropical Medicine
Swiss TPH
University of Basel
University of Milan

Research output: Contribution to journal › Comment/debate

29 Citations (Scopus)

Original language	English
Pages (from-to)	1357-1361
Number of pages	5
Journal	ChemMedChem
Volume	6
Issue number	8
DOIs	https://doi.org/10.1002/cmdc.201100196
Publication status	Published - 1 Aug 2011

Keywords

Antimalarial agents
Antiprotozoal agents
Hybrids
Peroxides
Tetraoxanes

Access to Document

10.1002/cmdc.201100196

Cite this

Chadwick, J., Amewu, R. K., Marti, F., Garah, F. B. E., Sharma, R., Berry, N. G., Stocks, P. A., Burrell-Saward, H., Wittlin, S., Rottmann, M., Brun, R., Taramelli, D., Parapini, S., Ward, S., & O'Neill, P. M. (2011). Antimalarial mannoxanes: hybrid antimalarial drugs with outstanding oral activity profiles and a potential dual mechanism of action. ChemMedChem, 6(8), 1357-1361. https://doi.org/10.1002/cmdc.201100196

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title = "Antimalarial mannoxanes: hybrid antimalarial drugs with outstanding oral activity profiles and a potential dual mechanism of action.",

keywords = "Antimalarial agents, Antiprotozoal agents, Hybrids, Peroxides, Tetraoxanes",

author = "James Chadwick and Amewu, \{Richard K.\} and Francesc Marti and Garah, \{Fatima Bousejra El\} and Raman Sharma and Berry, \{Neil G.\} and Stocks, \{Paul A.\} and Hollie Burrell-Saward and Sergio Wittlin and Matthias Rottmann and Reto Brun and Donatella Taramelli and Silvia Parapini and Steve Ward and O'Neill, \{Paul M.\}",

year = "2011",

month = aug,

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doi = "10.1002/cmdc.201100196",

language = "English",

volume = "6",

pages = "1357--1361",

journal = "ChemMedChem",

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Chadwick, J, Amewu, RK, Marti, F, Garah, FBE, Sharma, R, Berry, NG, Stocks, PA, Burrell-Saward, H, Wittlin, S, Rottmann, M, Brun, R, Taramelli, D, Parapini, S, Ward, S & O'Neill, PM 2011, 'Antimalarial mannoxanes: hybrid antimalarial drugs with outstanding oral activity profiles and a potential dual mechanism of action.', ChemMedChem, vol. 6, no. 8, pp. 1357-1361. https://doi.org/10.1002/cmdc.201100196

TY - JOUR

T1 - Antimalarial mannoxanes: hybrid antimalarial drugs with outstanding oral activity profiles and a potential dual mechanism of action.

AU - Chadwick, James

AU - Amewu, Richard K.

AU - Marti, Francesc

AU - Garah, Fatima Bousejra El

AU - Sharma, Raman

AU - Berry, Neil G.

AU - Stocks, Paul A.

AU - Burrell-Saward, Hollie

AU - Wittlin, Sergio

AU - Rottmann, Matthias

AU - Brun, Reto

AU - Taramelli, Donatella

AU - Parapini, Silvia

AU - Ward, Steve

AU - O'Neill, Paul M.

PY - 2011/8/1

Y1 - 2011/8/1

KW - Antimalarial agents

KW - Antiprotozoal agents

KW - Hybrids

KW - Peroxides

KW - Tetraoxanes

U2 - 10.1002/cmdc.201100196

DO - 10.1002/cmdc.201100196

M3 - Comment/debate

SN - 1860-7179

VL - 6

SP - 1357

EP - 1361

JO - ChemMedChem

JF - ChemMedChem

IS - 8

ER -