TY - JOUR
T1 - Anthropometric, biochemical, dietary, morbidity and wellbeing assessments in women and children in Indonesia, India and Senegal: a UKRI GCRF Action Against Stunting Hub protocol paper
AU - Davies-Kershaw, Hilary
AU - Fahmida, Umi
AU - Htet, Min Kyaw
AU - Kulkarni, Bharati
AU - Faye, Babacar
AU - Yanti, Dwi
AU - Shinta, Dewi
AU - Zahra, Nur L.
AU - Angelin, Tiffany C.
AU - Madhari, Radhika
AU - Pullakhandam, Raghu
AU - Palika, Ravindranadh
AU - Dasi, Teena
AU - Fernandez Rao, Sylvia
AU - Banjara, Santosh Kumar
AU - Selvaraj, Kiruthika
AU - Palepu, Dharani Pratyusha
AU - Yadev, Dinesh
AU - Diouf, Saliou
AU - Lopez-Sall, Philomene
AU - Diallo, Babacar
AU - Mouissi, Princillia
AU - Fall, Sally
AU - Diallo, Ibrahima
AU - Djigal, Aicha
AU - Immerzeel, Tabitha D.Van
AU - Tairou, Fassia
AU - Diop, Assana
AU - Pradeilles, Rebecca
AU - Strout, Sara
AU - Momo Kadia, Benjamin
AU - Tata, Darius Tetsa
AU - Jobarteh, Modou Lamin
AU - Allen, Stephen
AU - Walker, Alan
AU - Webster, Joanne P.
AU - Haggarty, Paul
AU - Heffernan, Claire
AU - Ferguson, Elaine
PY - 2024/2/27
Y1 - 2024/2/27
N2 - Introduction:Child-stunting has a complex aetiology, especially in the first 1000 days of life. Nutrition interventions alone have not produced expected impacts in reducing/preventing child-stunting, indicating the importance of understanding the complex interplay between environmental, physiological and psychological factors influencing child nutritional status. This study will investigate maternal and child nutrition, health and wellbeing status and associated factors through the assessment of:(1) anthropometry; (2) biomarkers of nutrition and health status; (3) dietary intakes; (4) fetal growth and development; (5) infant morbidity; (6) Infant and Young Child Feeding (IYCF); and (7) perinatal maternal stress, depression and social support.Methods: This study will be conducted in a prospective pregnancy cohort in India, Indonesia and Senegal. Pregnant women will be recruited in the second (Indonesia, Senegal) and third (India) trimester of pregnancy, and the mother and infant dyads followed until the infant is 24-months of age. During pregnancy, anthropometric measures will be taken, venous blood samples will be collected for biochemical assessment of nutrition and health status, dietary intakes will be assessed using a 4-pass-24-hour dietary recall method (MP24HR), fetal ultrasound for assessment of fetal growth. After birth, anthropometry measurements will be taken, venous blood samples will be collected, MP24HR will be conducted, infant morbidity and IYCF practices will be assessed and a sample of breastmilk will be collected for nutrient composition analyses. Perinatal maternal stress, depression, social support and hair cortisol levels (stress) will be measured. The results from this study will be integrated in an interdisciplinary analysis to examine factors influencing infant growth and inform global efforts in reducing child stunting. Ethics and dissemination: Ethical approval was granted by the Ethics Committee of the London School of Hygiene and Tropical Medicine (17915/RR/17513); National Institute of Nutrition (ICMR)- Ministry of Health and Family Welfare, Government of India (CR/04/I/2021); Health Research Ethics Committee, University of Indonesia and Cipto Mangunkusumo Hospital (KET-887/UN2.F1/ETIK/PPM.00.02/2019); and the Comité National d'Ethique pour la Recherche en Santé, Senegal (Protocole SEN19/78); the Royal Veterinary College (URN SR2020-0197); and the International Livestock Research Institute Institutional Research Ethics Committee (ILRI-IREC2020-33). Results will be published in peer-reviewed journals and disseminated to policy makers and participating communities.
AB - Introduction:Child-stunting has a complex aetiology, especially in the first 1000 days of life. Nutrition interventions alone have not produced expected impacts in reducing/preventing child-stunting, indicating the importance of understanding the complex interplay between environmental, physiological and psychological factors influencing child nutritional status. This study will investigate maternal and child nutrition, health and wellbeing status and associated factors through the assessment of:(1) anthropometry; (2) biomarkers of nutrition and health status; (3) dietary intakes; (4) fetal growth and development; (5) infant morbidity; (6) Infant and Young Child Feeding (IYCF); and (7) perinatal maternal stress, depression and social support.Methods: This study will be conducted in a prospective pregnancy cohort in India, Indonesia and Senegal. Pregnant women will be recruited in the second (Indonesia, Senegal) and third (India) trimester of pregnancy, and the mother and infant dyads followed until the infant is 24-months of age. During pregnancy, anthropometric measures will be taken, venous blood samples will be collected for biochemical assessment of nutrition and health status, dietary intakes will be assessed using a 4-pass-24-hour dietary recall method (MP24HR), fetal ultrasound for assessment of fetal growth. After birth, anthropometry measurements will be taken, venous blood samples will be collected, MP24HR will be conducted, infant morbidity and IYCF practices will be assessed and a sample of breastmilk will be collected for nutrient composition analyses. Perinatal maternal stress, depression, social support and hair cortisol levels (stress) will be measured. The results from this study will be integrated in an interdisciplinary analysis to examine factors influencing infant growth and inform global efforts in reducing child stunting. Ethics and dissemination: Ethical approval was granted by the Ethics Committee of the London School of Hygiene and Tropical Medicine (17915/RR/17513); National Institute of Nutrition (ICMR)- Ministry of Health and Family Welfare, Government of India (CR/04/I/2021); Health Research Ethics Committee, University of Indonesia and Cipto Mangunkusumo Hospital (KET-887/UN2.F1/ETIK/PPM.00.02/2019); and the Comité National d'Ethique pour la Recherche en Santé, Senegal (Protocole SEN19/78); the Royal Veterinary College (URN SR2020-0197); and the International Livestock Research Institute Institutional Research Ethics Committee (ILRI-IREC2020-33). Results will be published in peer-reviewed journals and disseminated to policy makers and participating communities.
KW - data collection
KW - epidemiology
KW - growth
U2 - 10.1136/bmjpo-2022-001683
DO - 10.1136/bmjpo-2022-001683
M3 - Article
SN - 2399-9772
VL - 8
SP - e001683
JO - BMJ Paediatrics Open
JF - BMJ Paediatrics Open
IS - Suppl 1
M1 - e001683
ER -