Advances in dissecting mosquito innate immune responses to arbovirus infection

Rennos Fragkoudis; Ghassem Attarzadeh-Yazdi; Anthony A. Nash; John K. Fazakerley; Alain Kohl

doi:10.1099/vir.0.013201-0

Advances in dissecting mosquito innate immune responses to arbovirus infection

Rennos Fragkoudis
, Ghassem Attarzadeh-Yazdi
, Anthony A. Nash
, John K. Fazakerley
, Alain Kohl

University of Edinburgh

Research output: Contribution to journal › Review article › peer-review

102 Citations (Scopus)

Abstract

Arthropod-borne viruses - arboviruses - are a significant threat to public health. Whilst there is considerable knowledge about arbovirus interactions with vertebrate immunity, relatively little is known about how vectors such as mosquitoes control arbovirus infections. In this review, we discuss novel findings in the field of mosquito antiviral responses to arboviruses, in particular RNA interference, the up-and-coming field of general immune-signalling pathways, and cell death/apoptosis.

Original language	English
Pages (from-to)	2061-2072
Number of pages	12
Journal	Journal of General Virology
Volume	90
Issue number	9
DOIs	https://doi.org/10.1099/vir.0.013201-0
Publication status	Published - 1 Jan 2009
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1099/vir.0.013201-0

Cite this

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abstract = "Arthropod-borne viruses - arboviruses - are a significant threat to public health. Whilst there is considerable knowledge about arbovirus interactions with vertebrate immunity, relatively little is known about how vectors such as mosquitoes control arbovirus infections. In this review, we discuss novel findings in the field of mosquito antiviral responses to arboviruses, in particular RNA interference, the up-and-coming field of general immune-signalling pathways, and cell death/apoptosis.",

author = "Rennos Fragkoudis and Ghassem Attarzadeh-Yazdi and Nash, \{Anthony A.\} and Fazakerley, \{John K.\} and Alain Kohl",

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AU - Fragkoudis, Rennos

AU - Attarzadeh-Yazdi, Ghassem

AU - Nash, Anthony A.

AU - Fazakerley, John K.

AU - Kohl, Alain

PY - 2009/1/1

Y1 - 2009/1/1

N2 - Arthropod-borne viruses - arboviruses - are a significant threat to public health. Whilst there is considerable knowledge about arbovirus interactions with vertebrate immunity, relatively little is known about how vectors such as mosquitoes control arbovirus infections. In this review, we discuss novel findings in the field of mosquito antiviral responses to arboviruses, in particular RNA interference, the up-and-coming field of general immune-signalling pathways, and cell death/apoptosis.

AB - Arthropod-borne viruses - arboviruses - are a significant threat to public health. Whilst there is considerable knowledge about arbovirus interactions with vertebrate immunity, relatively little is known about how vectors such as mosquitoes control arbovirus infections. In this review, we discuss novel findings in the field of mosquito antiviral responses to arboviruses, in particular RNA interference, the up-and-coming field of general immune-signalling pathways, and cell death/apoptosis.

U2 - 10.1099/vir.0.013201-0

DO - 10.1099/vir.0.013201-0

M3 - Review article

SN - 0022-1317

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SP - 2061

EP - 2072

JO - Journal of General Virology

JF - Journal of General Virology

IS - 9

ER -

Advances in dissecting mosquito innate immune responses to arbovirus infection

Abstract

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