TY - JOUR
T1 - Advances in dissecting mosquito innate immune responses to arbovirus infection
AU - Fragkoudis, Rennos
AU - Attarzadeh-Yazdi, Ghassem
AU - Nash, Anthony A.
AU - Fazakerley, John K.
AU - Kohl, Alain
PY - 2009/1/1
Y1 - 2009/1/1
N2 - Arthropod-borne viruses - arboviruses - are a significant threat to public health. Whilst there is considerable knowledge about arbovirus interactions with vertebrate immunity, relatively little is known about how vectors such as mosquitoes control arbovirus infections. In this review, we discuss novel findings in the field of mosquito antiviral responses to arboviruses, in particular RNA interference, the up-and-coming field of general immune-signalling pathways, and cell death/apoptosis.
AB - Arthropod-borne viruses - arboviruses - are a significant threat to public health. Whilst there is considerable knowledge about arbovirus interactions with vertebrate immunity, relatively little is known about how vectors such as mosquitoes control arbovirus infections. In this review, we discuss novel findings in the field of mosquito antiviral responses to arboviruses, in particular RNA interference, the up-and-coming field of general immune-signalling pathways, and cell death/apoptosis.
U2 - 10.1099/vir.0.013201-0
DO - 10.1099/vir.0.013201-0
M3 - Review article
SN - 0022-1317
VL - 90
SP - 2061
EP - 2072
JO - Journal of General Virology
JF - Journal of General Virology
IS - 9
ER -
