Acquired antibiotic resistance genes: An overview: An overview

Angela H.A.M. Van Hoek; Dik Mevius; Beatriz Guerra; Peter Mullany; Adam Roberts; Henk J.M. Aarts

doi:10.3389/fmicb.2011.00203

Acquired antibiotic resistance genes: An overview: An overview

Angela H.A.M. Van Hoek, Dik Mevius, Beatriz Guerra, Peter Mullany, Adam Roberts, Henk J.M. Aarts

Research output: Contribution to journal › Review article › peer-review

579 Citations (Scopus)

Abstract

In this review an overview is given on antibiotic resistance (AR) mechanisms with special attentions to the AR genes described so far preceded by a short introduction on the discovery and mode of action of the different classes of antibiotics. As this review is only dealing with acquired resistance, attention is also paid to mobile genetic elements such as plasmids, transposons, and integrons, which are associated with AR genes, and involved in the dispersal of antimicrobial determinants between different bacteria.

Original language	English
Journal	Frontiers in Microbiology
Volume	2
Issue number	SEP
DOIs	https://doi.org/10.3389/fmicb.2011.00203
Publication status	Published - 1 Jan 2011
Externally published	Yes

Keywords

Acquired
Antibiotics
Antimicrobial resistance mechanisms
Mobile genetic elements

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10.3389/fmicb.2011.00203

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title = "Acquired antibiotic resistance genes: An overview: An overview",

abstract = "In this review an overview is given on antibiotic resistance (AR) mechanisms with special attentions to the AR genes described so far preceded by a short introduction on the discovery and mode of action of the different classes of antibiotics. As this review is only dealing with acquired resistance, attention is also paid to mobile genetic elements such as plasmids, transposons, and integrons, which are associated with AR genes, and involved in the dispersal of antimicrobial determinants between different bacteria.",

keywords = "Acquired, Antibiotics, Antimicrobial resistance mechanisms, Mobile genetic elements",

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AU - Van Hoek, Angela H.A.M.

AU - Mevius, Dik

AU - Guerra, Beatriz

AU - Mullany, Peter

AU - Roberts, Adam

AU - Aarts, Henk J.M.

PY - 2011/1/1

Y1 - 2011/1/1

N2 - In this review an overview is given on antibiotic resistance (AR) mechanisms with special attentions to the AR genes described so far preceded by a short introduction on the discovery and mode of action of the different classes of antibiotics. As this review is only dealing with acquired resistance, attention is also paid to mobile genetic elements such as plasmids, transposons, and integrons, which are associated with AR genes, and involved in the dispersal of antimicrobial determinants between different bacteria.

AB - In this review an overview is given on antibiotic resistance (AR) mechanisms with special attentions to the AR genes described so far preceded by a short introduction on the discovery and mode of action of the different classes of antibiotics. As this review is only dealing with acquired resistance, attention is also paid to mobile genetic elements such as plasmids, transposons, and integrons, which are associated with AR genes, and involved in the dispersal of antimicrobial determinants between different bacteria.

KW - Acquired

KW - Antibiotics

KW - Antimicrobial resistance mechanisms

KW - Mobile genetic elements

U2 - 10.3389/fmicb.2011.00203

DO - 10.3389/fmicb.2011.00203

M3 - Review article

SN - 1664-302X

VL - 2

JO - Frontiers in Microbiology

JF - Frontiers in Microbiology

IS - SEP

ER -

Acquired antibiotic resistance genes: An overview: An overview

Abstract

Keywords

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