A clinical randomized controlled trial of music therapy and progressive muscle relaxation training in female breast cancer patients after radical mastectomy: Results on depression, anxiety and length of hospital stay

To examine effects of music therapy and progressive muscle relaxation training on depression, anxiety and length of hospital stay in Chinese female breast cancer patients after radical mastectomy. Methods: A total of 170 patients were randomly allocated to the intervention group (. n=85) receiving music therapy and progressive muscle relaxation training plus routine nursing care and the control group (. n=85) receiving routine nursing care. Music therapy and progressive muscle relaxation training were performed twice a day within 48h after radical mastectomy, once in the early morning (6a.m.-8a.m.) and once in the evening (9p.m.-11p.m.), for 30min per session until discharged from the hospital. Results: A general linear model with univariate analysis showed that the intervention group patients had significant improvement in depression and anxiety in the effects of group (. F=20.31, P<0.001; F=5.41, P=0.017), time (. F=56.64, P<0.001; F=155.17, P<0.001) and group * time interaction (. F=6.91, P=0.009; F=5.56, P=0.019). The intervention group patients had shorter length of hospital stay (12.56±1.03) than that of the control group (17.01±2.46) with statistical significance (. F=13.36, P<0.001). Conclusion: Music therapy and progressive muscle relaxation training can reduce depression, anxiety and length of hospital stay in female breast cancer patients after radical mastectomy.