Personal profile
Biography
Professor Tony Nolan began his career at Imperial College, where he earned a BSc in Applied Biology and completed a PhD focused on developing transformation technologies for malaria mosquito vectors. His postdoctoral research at the University of Rome "La Sapienza" and University College London explored genome defence mechanisms and the biology of ageing. He later joined the Target Malaria research consortium as a Senior Research Fellow, where he developed gene drives to control malaria mosquitoes. Moving to Liverpool School of Tropical Medicine (LSTM) in 2019, he established an independent research group and, in 2023, was appointed to Chair in Functional Genetics, focusing on innovative genetic tools and strategies for mosquito control. Professor Nolan also serves as Head of LSTM's Department of Vector Biology, one of the largest of its kind, encompassing over 20 research groups looking at various aspects of vector-borne disease biology and transmission.
Professor Nolan is a Fellow of the Higher Education Academy and served as the Vice-Chair of the Scientific Committee for the Association for Responsible Research in Genome Editing from 2021 to 2022. He was also a Springboard Fellow of the Academy of Medical Science from 2021 to 2023.
Research interests
Professor Nolan's main research interests are vector behaviour and genomics, insecticide resistance, vector pathogen interactions, and vector control.
The Functional Genetics group's research focuses on three areas: genetic control of mosquito populations to reduce malaria transmission, development of functional genetics tools for the study of key mosquito traits (such as insecticide resistance, mosquito fertility, bloodmeal digestion etc.), and developing and sharing capacity around the molecular biology and genetics, including both knowledge and practical infrastructure, that is needed to accompany the implementation and monitoring of vector control programmes.
The group has active research collaborations in the UK with Liverpool John Moores University, Keele University, Imperial College London; in Italy with PoloGGB at Terni and University of Rome "La Sapienza"; and worldwide with Institut de Recherche en Sciences de la Santé, Burkina Faso, University of Sciences, Techniques and Technologies of Bamako, Mali, the Uganda Virus Research Institute, and Ifakara Health Research Institute, Tanzania.
Teaching
Professor Nolan is Co-director of the MRes in Tropical Health and Infectious Disease Research and lectures on the MSc in Tropical Disease Biology, Diploma in Tropical Medicine and Hygiene, and BSc in Tropical Disease Biology (University of Liverpool).
Themes
- Innovation to Impact: Therapeutics, Diagnostics, Vaccines
- Malaria and Neglected Tropical Diseases
- Vector Control and Resistance Management
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Updating Anopheles funestus group members in Burkina Faso species distribution and contribution to malaria transmission
Zongo, O. N., Toé, I., Kientega, M., Yemien, S. O. G., Sawadogo, G., Kaboré, H., Agolinou, A. A. M., Traore, N., Kiendrebeogo, E., Millogo, A. A., Niang, A., Namountougou, M., Lanfrancotti, A., Nolan, T., Maiga, H. & Diabaté, A., 3 Feb 2026, In: Malaria Journal. 25, 1, 130.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
A Y chromosome-linked genome editor for efficient population suppression in the malaria vector Anopheles gambiae
Tolosana, I., Willis, K., Gribble, M., Phillimore, L., Burt, A., Nolan, T., Crisanti, A. & Bernardini, F., 2 Jan 2025, In: Nature Communications. 16, 1, p. 206 206.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus) -
Temporal and spatial profiling of Aedes albopictus immune responses to chikungunya virus infection
Dipaola, M. G., Fortuna, C., Severini, F., Bevivino, G., Di Luca, M., Nolan, T., Salvemini, M., Arcà, B. & Lombardo, F., 3 Oct 2025, In: PLoS Neglected Tropical Diseases. 2025-October, 10, p. e0013588 e0013588.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Corrigendum: A mosquito small RNA genomics resource reveals dynamic evolution and host responses to viruses and transposons
Ma, Q., Srivastav, S. P., Gamez, S., Dayama, G., Feitosa-Suntheimer, F., Patterson, I., Johnson, R. M., Matson, E. M., Gold, A. S., Brackney, D. E., Connor, J. H., Colpitts, T. M., Hughes, G., Rasgon, J. L., Nolan, T., Akbari, O. S. & Lau, N. C., 7 Feb 2024, 1 p.Research output: Other contribution
Open Access -
CRISPR/Cas9-mediated mutation of nicotinic acetylcholine receptor (nAChR) α subunit confers moderate levels of resistance to spinosad and imidacloprid in the natural predator Coccinella septempunctata without fitness cost
Guo, X., Zhang, L., Wang, M., Li, Y., Shen, Z., Nolan, T. & Mao, J., 30 Sept 2024, In: Entomologia Generalis. 44, 4, p. 1059-1067 9 p., ESP146004404025.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus)
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