Personal profile
Biography
Stephen Spencer is an intensive care and acute medicine specialist registrar and Wellcome Trust Clinical PhD Fellow at the Malawi-Liverpool-Wellcome Programme. As a medical student at the University of Manchester, he founded an international health research charity in rural and remote areas of Madagascar, where he led and conducted community-based observational research. Prior to his PhD Fellowship, he completed a distance learning MSc in Epidemiology with distinction at the London School of Hygiene and Tropical Medicine, and Diploma of Tropical Medicine and Hygiene at Liverpool School of Tropical Medicine (LSTM).
Research interests
Stephen’s research focuses on breathlessness, complex care and acute care service design in low-resource settings. During his PhD Fellowship he worked as clinical lead in Malawi on the National Institute for Health and Care Research Multilink study (Multimorbidity-associated emergency hospital admissions; a “screen and link” strategy to improve outcomes for high-risk patients in sub-Saharan Africa) and delivered this multicentre study to time and target. During this time, he also led the Breathlessness in Sub-Saharan Africa study as principal investigator. The study was designed to understand evolving clinical phenotypes and pathophysiology of acute severe illness, with a focus on breathlessness syndromes to develop context-appropriate diagnostic approaches and design integrated care pathways. Stephen also oversees the ultrasound arm of the Building Respiratory support in East Africa Through High flow versus low flow oxygen Evaluation trial in Malawi and collaborates on the African Research Collaboration on Sepsis.
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Collaborations and top research areas from the last five years
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One-year follow-up of survival and health-related quality of life in patients with medical conditions admitted acutely to hospital in Malawi and Tanzania
the Multilink Consortium, Yongolo, N. M., Simiyu, I. G., Spencer, S. A., Worrall, E. & Morton, B., 1 Feb 2026, In: Anaesthesia. 81, 2, p. 297-299 3 p.Research output: Contribution to journal › Letter › peer-review
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Perspectives on multimorbidity care provision among public hospital-based healthcare workers in Blantyre and Chiradzulu, Malawi A qualitative study
on behalf of the Multilink consortium, Banda-Mtaula, G. T., Simiyu, I., Salimu, S. N., Spencer, S. A., Yongolo, N. M., Chawani, M., Sawe, H., Rylance, J., Morton, B., Muula, A. S., Worall, E., Limbani, F., Taegtmeyer, M. & Mijumbi, R., 2 Apr 2026, In: PLoS ONE. 21, 4, e0346493.Research output: Contribution to journal › Article › peer-review
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Acute breathlessness as a cause of hospitalisation in Malawi: A prospective, patient-centred study to evaluate causes and outcomes
Collaborators, Spencer, S. A., Malowa, F., McCarty, D., Joekes, E., Phulusa, J., Chinoko, B., Kaimba, S., Keyala, L., Mandala, P., Mkandawire, M., Mukatipa, A., Nyirenda, M., Sawe, H. R., White, S. A., Henrion, M. Y. R., Augustine, D. X., Oxborough, D., Worrall, E. & Limbani, F. & 4 others, , 10 Sept 2025, (E-pub ahead of print) In: Thorax.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus) -
Causes, outcomes and diagnosis of acute breathlessness hospital admissions in Malawi: protocol for a multicentre prospective cohort study
Spencer, S., Malowa, F., McCarty, D., Joekes, E., Phulusa, J., Chinoko, B., Kaimba, S., Keyala, L., Mandala, P., Mkandawire, M., Mlongoti, M., Mnesa, B., Mukatipa, A., Mijumbi, R., Nyirenda, M., Sawe, H. R., Henrion, M., Augustine, D. X., Oxborough, D. & Worrall, E. & 5 others, , 17 Apr 2024, In: Wellcome Open Research. 9, 205.Research output: Contribution to journal › Article › peer-review
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Interdisciplinary perspectives on multimorbidity in Africa: Developing an expanded conceptual model
Dixon, J., Morton, B., Nkhata, M. J., Silman, A., Simiyu, I., Spencer, S., Van Pinxteren, M., Bunn, C., Calderwood, C., Chandler, C. I. R., Chikumbu, E., Crampin, A. C., Hurst, J. R., Jobe, M., Kengne, A. P., Levitt, N. S., Moshabela, M., Owolabi, M., Peer, N. & Phiri, N. & 42 others, , 30 Jul 2024, In: PLOS Global Public Health. 4, 7, p. e0003434 e0003434.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)
Thesis
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Acute multimorbid hospital presentations and breathlessness in sub-Saharan Africa
Spencer, S. (Author), Rylance, J. (Supervisor), Morton, B. (Supervisor), Gordon, S. (Supervisor) & Dark, P. (Supervisor), 24 Oct 2025Student thesis: Doctoral thesis
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