Sophie's interests lie in epidemiology, disease control and public health. She is drawn predominantly to operational research questions, seeking to understand programmatic problems, find solutions, and optimise procedures. She is focused on contributing to an immediate and lasting impact to public health programmes.

Sophie leads the short course on making maps for public health, is co-convenor on the development of a disease control programme module, and contributes to teaching on other modules on subjects such as geographic information systems and vector control. In addition to teaching at LSTM, she also designs and delivers bespoke training to disease surveillance and control staff in English, French and Spanish.