Research output per year
Research output per year
Personal profile
Biography
Shree Hegde completed her PhD at the University of Vienna, including a dissertation carried out at University of Veterinary Medicine. Her PhD research elucidated novel molecular and cellular mechanisms facilitating the successful infection of opportunistic ruminant pathogen mycoplasma agalctiae. Following this, she joined the University of Texas Medical Branch as a postdoctoral fellow to study the role of gut microbiota and bacterial infection during functional colon motility disorders.
In January 2021, Shree joined the Centre for Drugs and Diagnostics at the Liverpool School of Tropical Medicine to work towards developing new diagnostics tools and therapeutic treatments for human and zoonotic filarial infections.
Research interests
Shree’s wider research interest is in infection biology, particularly studying host-pathogen/parasite interaction. Currently she is working with experts in interdisciplinary areas and international partner organisations to develop novel and affordable anti-wolbachia curative treatment for filarial infections. She is part of a multi-disciplinary team developing an innovative non-invasive diagnostic tool for human lymphatic filariasis. Shree is also currently leading a research programme funded by UK Research and Innovation to investigate therapeutic potential of bioactive lipids in treatment of filarial immunopathologies
Teaching
Shree undertakes a supervisor role for MSc and MRes research projects and supports the a module covering lymphatic filariasis biology.
Education/Academic qualification
PhD, New Insights into the Molecular and Cellular Mechanisms of Mycoplasma agalactiae Pathogenesis, University of Vienna
Award Date: 1 Jan 2016
Themes
- Malaria and Neglected Tropical Diseases
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Diverse RNA viruses of parasitic nematodes can elicit antibody responses in vertebrate hosts
Quek, S., Hadermann, A., Wu, Y., De Coninck, L., Hegde, S., Boucher, J. R., Cresswell, J., Foreman, E., Steven, A., LaCourse, J., Ward, S., Wanji, S., Hughes, G., Patterson, I., Wagstaff, S., Turner, J., Parry, R. H., Kohl, A., Heinz, E. & Otabil, K. B. & 3 others, , 4 Sept 2024, In: Nature Microbiology. 9, 10, p. 2488-2505 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus) -
Combinations of the azaquinazoline anti-Wolbachia agent, AWZ1066S, with benzimidazole anthelmintics synergise to mediate sub-seven-day sterilising and curative efficacies in experimental models of filariasis
Hegde, S., Marriott, A., Pionnier, N., Steven, A., Bulman, C., Gunderson, E., Vogel, I., Koschel, M., Ehrens, A., Lustigman, S., Voronin, D., Tricoche, N., Hoerauf, A., Hübner, M. P., Sakanari, J., Aljayyoussi, G., Gusovsky, F., Dagley, J., Hong, D. W. & O'Neill, P. & 3 others, , 1 Feb 2024, In: Frontiers in Microbiology. 15, p. 1346068 1346068.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus) -
Dirofilariasis mouse models for heartworm preclinical research
Marriott, A., Dagley, J., Hegde, S., Steven, A., Fricks, C., DiCosty, U., Mansour, A., Campbell, E. J., Wilson, C. M., Gusovsky, F., Ward, S., Hong, W. D., O'Neill, P., Moorhead, A., McCall, S., McCall, J. W., Taylor, M. & Turner, J., 22 Jun 2023, In: Frontiers in Microbiology. 14, p. e1208301 1208301.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus) -
Effects of Coffee on Gut Microbiota and Bowel Functions in Health and Diseases: A Literature Review
Saygili, S., Hegde, S. & Shi, X. Z., 18 Sept 2024, In: Nutrients. 16, 18, p. 3155 3155.Research output: Contribution to journal › Review article › peer-review
Open AccessFile38 Citations (Scopus) -
Effects of coffee on gut microbiota in health and diseases
Hegde, S. & Shi, X. Z., 1 Jan 2024, Coffee in Health and Disease Prevention. Elsevier, p. 431-441 11 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
2 Citations (Scopus)