Personal profile
Biography
Research interests
Shree’s wider research interest is in infection biology, particularly studying host-pathogen/parasite interaction. Currently she is working with experts in interdisciplinary areas and international partner organisations to develop novel and affordable anti-wolbachia curative treatment for filarial infections. She is part of a multi-disciplinary team developing an innovative non-invasive diagnostic tool for human lymphatic filariasis. Shree is also currently leading a research programme funded by UK Research and Innovation to investigate therapeutic potential of bioactive lipids in treatment of filarial immunopathologies
Teaching
Shree undertakes a supervisor role for MSc and MRes research projects and supports the a module covering lymphatic filariasis biology.
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Collaborations and top research areas from the last five years
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Combinations of the azaquinazoline anti-Wolbachia agent, AWZ1066S, with benzimidazole anthelmintics synergise to mediate sub-seven-day sterilising and curative efficacies in experimental models of filariasis
Hegde, S., Marriott, A., Pionnier, N., Steven, A., Bulman, C., Gunderson, E., Vogel, I., Koschel, M., Ehrens, A., Lustigman, S., Voronin, D., Tricoche, N., Hoerauf, A., Hübner, M. P., Sakanari, J., Aljayyoussi, G., Gusovsky, F., Dagley, J., Hong, D. W. & O'Neill, P. & 3 others, , 1 Feb 2024, In: Frontiers in Microbiology. 15, p. 1346068 1346068.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus) -
Diverse RNA viruses of parasitic nematodes can elicit antibody responses in vertebrate hosts
Quek, S., Hadermann, A., Wu, Y., De Coninck, L., Hegde, S., Boucher, J. R., Cresswell, J., Foreman, E., Steven, A., LaCourse, J., Ward, S., Wanji, S., Hughes, G., Patterson, I., Wagstaff, S., Turner, J., Parry, R. H., Kohl, A., Heinz, E. & Otabil, K. B. & 3 others, , 4 Sept 2024, In: Nature Microbiology. 9, 10, p. 2488-2505 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus) -
Effects of Coffee on Gut Microbiota and Bowel Functions in Health and Diseases: A Literature Review
Saygili, S., Hegde, S. & Shi, X. Z., 18 Sept 2024, In: Nutrients. 16, 18, p. 3155 3155.Research output: Contribution to journal › Review article › peer-review
Open AccessFile26 Citations (Scopus) -
Dirofilariasis mouse models for heartworm preclinical research
Marriott, A., Dagley, J., Hegde, S., Steven, A., Fricks, C., DiCosty, U., Mansour, A., Campbell, E. J., Wilson, C. M., Gusovsky, F., Ward, S., Hong, W. D., O'Neill, P., Moorhead, A., McCall, S., McCall, J. W., Taylor, M. & Turner, J., 22 Jun 2023, In: Frontiers in Microbiology. 14, p. e1208301 1208301.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus) -
Mechanisms of lymphoid depletion in bowel obstruction
Lin, Y. M., Hegde, S., Cong, Y. & Shi, X. Z., 21 Sept 2022, In: Frontiers in Physiology. 13, p. e1005088 1005088.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)