Personal profile
Biography
Shevin Jacob is an infectious diseases physician and Reader in Sepsis Research in the Department of Clinical Sciences at the Liverpool School of Tropical Medicine (LSTM). He obtained his Doctorate of Medicine (MD) from Oregon Health & Science University and a Master of Public Health (MPH) degree from the Harvard T.H. Chan School of Public Health. Shevin completed internal medicine residency training at the University of Virginia and infectious diseases fellowship training at the University of Washington, where he later held a faculty role in the Division of Allergy and Infectious Diseases before joining LSTM in 2017. He currently lives in Uganda which has been his research base since 2006.
Shevin is Co-Founder and a Director of Walimu, a non-government organisation registered in Uganda that oversees and implements research (primarily in areas of sepsis and tuberculosis) and programmatic activities (including strengthening health workforce capacity for management of viral haemorrhagic fevers and other infectious diseases outbreaks). He is also Secretary General and Executive Committee Member for the African Sepsis Alliance, Board and Executive Committee Member for the Global Sepsis Alliance, Consultant to the World Health Organisation, on a wide range of sepsis-related topics, and currently serves as a Chair for the Research Ethics Committee at LSTM.
In 2018, Shevin received the Leadership in Public Health Practice Harvard Alumni Award for his work in sepsis and viral haemorrhagic fevers.
Research interests
Shevin’s research aims to improve understanding of the epidemiology, pathogenesis and clinical management of severe infections, including viral haemorrhagic fevers, among adults from resource-constrained settings across sub-Saharan Africa. As part of his research portfolio, he has led multinational consortia that focus on strengthening sepsis research capacity in sub-Saharan Africa to uncover and address knowledge gaps along the patient care continuum. Other areas of research include antimicrobial resistance and non-communicable diseases.
Currently, Shevin is the Chief Scientific Officer for the Sub-Saharan African ConsorTium for the Advancement of Innovative Research and Care in Sepsis, a multinational 5-year programme funded by the German Federal Ministry of Education and Research. The programme comprises ten partners from seven countries, Sierra Leone, Ghana, Nigeria, Democratic Republic of the Congo, Uganda, Ethiopia, and Mozambique and two universities in Germany, and it collaborates with a wider network of healthcare leaders, researchers, and policy experts from across Sub-Saharan African, Europe (including LSTM) and North America.
The programme aims to enhance estimates of sepsis epidemiology at community and household levels, establish a multinational observational patient cohort of children and adults hospitalised with sepsis, evaluate the impact on processes of care and survival of a comprehensive sepsis diagnostic platform for use at patients’ bedsides, refine and evaluate the role of an electronic quality improvement mobile application on processes of care for sepsis and survival, and evaluate whether an interactive mobile phone-based patient intervention can reduce post-discharge mortality of adult patients hospitalised with sepsis.
Teaching
At LSTM, Shevin has integrated real-world clinical and research experience to develop and provide modules on sepsis and viral haemorrhagic fevers as part of LSTM’s Diploma in Tropical Medicine & Hygiene course. He also contributes to the LSTM postgraduate programme through mentorship of PhD students. To foster collaboration and inspire interest in global sepsis research, he supervises six LSTM PhD students from diverse backgrounds, including England, Italy, and several sub-Saharan African countries. He also serves as a member on several Progress Assessment Panels for other PhD students matriculating at LSTM.
In addition to teaching at LSTM, his commitment to education extends to capacity-building initiatives aimed to strengthen local expertise in sepsis and viral haemorrhagic fevers care and research across sub-Saharan Africa through pre-service and in-service courses, including ones led by the World Health Organisation and London School of Hygiene & Tropical Medicine.
Themes
- Community Health and Resilient Health Systems
- Innovation to Impact: Therapeutics, Diagnostics, Vaccines
- Tuberculosis and Antimicrobial Resistance
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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An automated and portable platform for rapid cell-free DNA isolation and its application in microbial DNA metagenomic sequencing from human blood samples
Marriott, L., Martinez-Lopez, A., Liga, A., Horiba, K., Warr, A., Phulusa, J. N., Kumar, R. S., Carey, L., Ito, Y., Parcell, B. J., Leslie, N. R., Feasey, N. A., Jacob, S. T., Rylance, J. & Kersaudy-Kerhoas, M., 6 Feb 2026, (Accepted/In press) In: Lab on a Chip. 26, 9, p. 2849-2860 12 p.Research output: Contribution to journal › Article › peer-review
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Medical oxygen and respiratory support requirements for patients hospitalised with COVID-19 in 23 low-income and middle-income countries: a prospective, observational cohort study
O2CoV2 investigators, Relan, P., Rylance, J., Arabi, Y. M., Convocar, P., Rolland, M. & Diaz, J. V., 7 Jan 2026, In: The Lancet Global Health. 14, 2, p. e233-e241Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Adaptive Design for Phase II/III Platform Trial of Lassa Fever Therapeutics
Bourner, J., Vaillant, M., Salam, A. P. A., Jaspard, M., Fritzell, C., Jacob, S., Fletcher, T., Ramharter, M., Ajayi, N., Okogbenin, S., Erameh, C., Grant, D., Samuels, R., Ayodeji, O. O., Sprecher, A., Gonçalves, B. P., Edwards, T. & Olliaro, P., 21 Jan 2025, In: Emerging Infectious Diseases. 31, 2, p. e9-e16Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Delayed correct diagnoses in emerging disease outbreaks: Historical patterns and lessons for contemporary responses
Pellejero-Sagastizábal, G., Bulescu, C., Gupta, N., Jokelainen, P., Gkrania-Klotsas, E., Barac, A., Goorhuis, A., Jacob, S., Agnandji, S. T., Ntoumi, F., Mora-Rillo, M., Paño-Pardo, J. R., Lescure, F. X. & Grobusch, M. P., 1 Aug 2025, In: Clinical Microbiology and Infection. 31, 8, p. 1298-1306 9 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile6 Citations (Scopus) -
Early warning systems for identifying severe maternal outcomes: findings from the WHO global maternal sepsis study: findings from the WHO global maternal sepsis study
Chimwaza, Y., Hunt, A., Oliveira-Ciabati, L., Bonnett, L., Abalos, E., Cuesta, C., Souza, J. P., Bonet, M., Brizuela, V., Lissauer, D., Mohammad Iqbal Aman, I. A., Noormal, B., Espinoza, M., Pasquale, J., Leroy, C., Roelens, K., Vandenberghe, G., Urlyss Agossou, M. C., Keke, S. G. & Aguemon, C. T. & 30 others, , 1 Jan 2025, In: eClinicalMedicine. 79, 102981.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus)