Personal profile
Biography
After obtaining a BSc in Neuroscience from the University of Manchester Rohit Patel completed MRes and PhD degrees at the University of Nottingham specialising in neuropharmacology. He joined the Centre for Snakebite Research & Interventions at the Liverpool School of Tropical Medicine in 2020 as a postdoctoral research associate and works under Prof Nicholas Casewell and Dr Cassandra Modahl.
Research interests
Rohit’s research involves investigating neurotoxic snake venom toxins from the ‘three-finger toxin’ family to find out what the most medically important toxins are and how they function. These toxins mainly target the nicotinic acetylcholine receptor at the neuromuscular junction to cause muscular paralysis. Inhibitors of these toxins are also assessed to determine their potential as treatments for neurotoxic snakebite. His interests also lie in investigating the mechanisms of action of toxins and other agents that cause neuronal damage.
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
Practical progress towards the development of recombinant antivenoms for snakebite envenoming
Menzies, S., Patel, R. & Ainsworth, S., 29 Apr 2025, In: Expert Opinion on Drug Discovery. 20, 6, p. 799-819 21 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile5 Citations (Scopus) -
Plug and play virus-like particles for the generation of anti-toxin antibodies
Edge, B., Marriott, A., Stars, E., Patel, R., Wilkinson, M., King, L. D. W., Slagboom, J., Tan, C. H., Ratanabanangkoon, K., Draper, S. J. & Ainsworth, S., 29 Aug 2024, In: Toxicon: X. 23, p. e100204 100204.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus) -
Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins
Khalek, I. S., Laxme, R. R. S., Nguyen, Y. T. K., Khochare, S., Patel, R., Woehl, J., Smith, J. M., Saye-Francisco, K., Kim, Y., Mindrebo, L. M., Tran, Q., Kędzior, M., Boré, E., Limbo, O., Verma, M., Stanfield, R. L., Menzies, S., Ainsworth, S., Harrison, R. & Burton, D. R. & 5 others, , 21 Feb 2024, In: Science Translational Medicine. 16, 735, eadk1867.Research output: Contribution to journal › Article › peer-review
Open AccessFile48 Citations (Scopus) -
An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules
Patel, R., Clare, R., Ledsgaard, L., Nys, M., Kool, J., Laustsen, A. H., Ulens, C. & Casewell, N., 20 Aug 2023, In: Biochemical Pharmacology. 216, p. e115758 115758.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus) -
Machine-learning guided Venom Induced Dermonecrosis Analysis tooL: VIDAL
Laprade, W., Bartlett, K., Christensen, C. R., Kazandjian, T., Patel, R., Crittenden, E., Dawson, C., Mansourvar, M., Wolff, D. S., Fryer, T., Laustsen, A. H., Casewell, N., Gutiérrez, J. M., Hall, S. R. & Jenkins, T. P., 8 Dec 2023, In: Scientific Reports. 13, 1, p. e21662 21662.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)
Datasets
-
Dataset for the article: Machine-learning guided Venom Induced Dermonecrosis Analysis tooL: VIDAL
Laprade, W. (Creator), Bartlett, K. (Creator), Kazandjian, T. (Creator), Patel, R. (Creator), Crittenden, E. (Creator), Dawson, C. (Creator), Casewell, N. (Creator) & Hall, S. (Creator), tbc, 23 Nov 2023
Dataset