Murielle Wondji, earned a BSc (Hons) in Biomedical Science from Liverpool John Moores University. She then joined the Liverpool School of Tropical Medicine (LSTM) as a Laboratory Technician in the Vector Biology department, Wondji Group, led by Professor Charles Wondji. Currently, as part of the LSTM research unit based at The Centre for Research in Infectious Diseases, Cameroon, she works as the Laboratory Manager, overseeing activities and research projects.

Additionally, Murielle is pursuing a part-time PhD in insecticide resistance, a major challenge in the fight against malaria eradication. Her current research focuses on the mechanisms of mosquitoes, malaria vectors, that allow them to withstand exposure to World Health Organisation-recommended insecticides.

As part of her PhD research, Murielle is investigating the role of ATP-Binding Cassette transporters in insecticide resistance in major African malaria vectors. These transporters are phase III metabolism enzymes.

She is interested in assessing their role in insecticide resistance in field populations of anopheles funestus s.s. and anopheles gambiae s.s. analysing their phenotypic response to insecticides, with and without pre-exposure to specific synergists.

Murielle is also conducting transcriptomic profiling analysis to study the expression of ATP-Binding Cassette transporters in A. funestus s.s. and A. gambiae s.s. particularly in populations resistant to pyrethroid insecticides. This is achieved through RNA-Seq data and qRT-PCR for candidate identification.

A phylogenetic analysis of key ATP-Binding Cassette transporters associated with resistance across Africa is performed, and the genetic variants that may drive ATP-Binding Cassette transporter-mediated resistance are explored. The candidate will be functionally validated using in vivo RNA interference (RNAi)and GAL4/UAS transgenesis approaches.