Research output per year
Research output per year
Personal profile
Biography
Michael Abouyannis is an Infectious Diseases Registrar based at the Royal Liverpool University Hospital and the Liverpool School of Tropical Medicine. He studied medicine at the University of Birmingham. His clinical experience includes junior and registrar training in Liverpool, emergency medicine and obstetrics in KwaZulu-Natal, and work as a clinician with Médecins Sans Frontières on the Uganda/Sudan border. His past academic experience includes HIV research at the Infectious Diseases Institute in Kampala, and TB and sepsis research in Malawi. Michael’s current research is focussed on early stage clinical trials to develop novel treatments for snakebite envenoming.
Research interests
Michael's main research focuses are snakebite, early phase clinical trials, and drug repurposing.
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Collaborations and top research areas from the last five years
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Development of an oral regimen of unithiol for the treatment of snakebite envenoming: a phase 1 open-label dose-escalation safety trial and pharmacokinetic analysis in healthy Kenyan adults.
Abouyannis, M., Nyambura, Y. K., Ngome, S., Riako, D., Musyoki, J., Muiruri, C., Orindi, B., Else, L., Amara, A., Dickinson, L., Clare, R., Albulescu, L.-O., Westhorpe, A., Kool, J., Adetifa, I., Ndungu, F. M., FitzGerald, R., Khoo, S., Lalloo, D. & Casewell, N. & 1 others, , 27 Feb 2025, In: eBioMedicine. 113, p. e105600 105600.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus) -
Handheld point-of-care devices for snakebite coagulopathy: a scoping review
Abouyannis, M., Marriott, A., Stars, E., Kitchen, D. P., Kitchen, S., Woods, T. A. L., Kreuels, B., Amuasi, J. H., Monteiro, W. M., Stienstra, Y., Senthilkumaran, S., Isbister, G. K., Lalloo, D., Ainsworth, S. & Casewell, N., 1 May 2025, In: Thrombosis and Haemostasis. 125, 5, p. 405-420 16 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile2 Citations (Scopus) -
Target product profiles for pan-Africa recombinant antivenoms against neurotoxic or hemotoxic and cytotoxic snakebite envenoming
Laustsen, A. H., Benard-Valle, M., Habib, A. G., Casewell, N., Abouyannis, M., Lalloo, D. & Ljungars, A., 24 Jan 2025, In: PLoS Neglected Tropical Diseases. 19, 1, p. e0012833 e0012833.Research output: Contribution to journal › Comment/debate
Open AccessFile2 Citations (Scopus) -
African polyvalent antivenom can maintain pharmacological stability and ability to neutralise murine venom lethality for decades post-expiry: evidence for increasing antivenom shelf life to aid in alleviating chronic shortages
Solano, G., Cunningham, S., Edge, B., Duran, G., Sanchez, A., Villalta, M., Clare, R., Wilkinson, M., Marriott, A., Abada, C., Menzies, S., Keen, M., Lalloo, D., Stienstra, Y., Abouyannis, M., Casewell, N., León, G. & Ainsworth, S., 13 Mar 2024, In: BMJ Global Health. 9, 3, p. e014813 e014813.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus) -
A global core outcome measurement set for snakebite clinical trials.
Abouyannis, M., Esmail, H., Hamaluba, M., Ngama, M., Mwangudzah, H., Mumba, N., Yeri, B. K., Mwalukore, S., Alphan, H. J., Aggarwal, D., Alcoba, G., Cammack, N., Chippaux, J. P., Coldiron, M. E., Gutiérrez, J. M., Habib, A. G., Harrison, R., Isbister, G. K., Lavonas, E. J. & Martins, D. & 15 others, , 18 Jan 2023, In: The Lancet Global Health. 11, 2, p. e296-e300Research output: Contribution to journal › Review article › peer-review
Open AccessFile30 Citations (Scopus)
Datasets
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Dataset for the article: A long-term observational study of paediatric snakebite in Kilifi County, south-east Kenya
Abouyannis, M. (Creator), Boga, M. (Creator), David, A. (Creator), Ouma, N. (Creator), Nyaguara, A. (Creator), Mturi, N. (Creator), Berkley, J. A. (Creator), Adetifa, I. M. (Creator), Casewell, N. R. (Creator), Lalloo, D. (Creator) & Hamaluba, M. (Creator), tbc, 17 Jul 2023
DOI: 10.1371/journal.pntd.0010987.s002
Dataset
Thesis
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Development of a repurposed orally available small molecule snakebite therapeutic: clinical need, safety, pharmacokinetics, and proposed methods to assess efficacy
Abouyannis, M. (Author), Casewell, N. (Supervisor), Lalloo, D. (Supervisor) & Hamaluba, M. (Supervisor), 2024Student thesis: Doctoral thesis
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