Personal profile
Biography
Martin James Donnelly is Professor of Evolutionary Genetics at Liverpool School of Tropical Medicine (LSTM). He is also an Honorary Faculty Member on the Malaria Programme, at the Wellcome Trust Sanger Institute,
Martin trained at Girton College, Cambridge University and LSTM. He then spent two years in the laboratory of Dr Tovi Lehmann at the Centers for Disease Control and Prevention, Atlanta, on an American Society of Microbiology Fellowship, before re-joining LSTM in the Department of Vector Biology in 2001.
Research interests
A major area of interest for Martin is the evolution of insecticide resistance in the malaria mosquito anopheles gambiae. He uses a variety of approaches to identify and validate insecticide resistance associated loci. Much of this work is conducted jointly with Dr David Weetman and team.
A second research area is understanding the impact of insecticide resistance on malaria epidemiology, through observational studies and randomised control trials.
In collaboration with Professor Dominic Kwiatkowski at the Wellcome Sanger Institute, Martin leverages the power of next-generation sequencing technologies to address aspects of the biology of anopheles gambiae that impact the sustainable control of malaria.
With Drs. Eric Ochomo and Ben Abong’o at KEMRI, Kisumu, Martin works on a range of basic and translational science projects including vector control trials and machine learning approaches for identifying insecticide resistant variants in genomic and transcriptomic data sets. With Dr. Luigi Sedda, at Lancaster University (https://www.lancaster.ac.uk/health-and-medicine/about-us/people/luigi-sedda) Martin works on development of spatially explicit sampling frameworks for vectors including adaptive sampling.
With Drs. Catherine Moyes and Penny Hancock from the Big Data Institute, University of Oxford Martin works on geospatial modelling of insecticide resistance.
With Professors Moses Kamya and Sarah Staedke from International Development Research Centre Uganda Martin works on the LLINEUP trial of next generation insecticide treated bednets.
And with Dr Luc Djogbenou based at the Institut Régional de Santé Publique/University of Abomey-Calavi Martin is addresses the interaction between insecticide resistance and vectorial ability in anopheles gambiae.
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Collaborations and top research areas from the last five years
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Mitochondrial genome analysis and molecular identification of two Culex tritaeniorhynchus (Diptera: Culicidae) clades from the Republic of Korea
Jeon, J., Donnelly, M. J. & Choi, K. S., 22 Jan 2026, In: Journal of Medical Entomology. 63, 1, tjaf192.Research output: Contribution to journal › Article › peer-review
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Attractive targeted sugar baits for malaria control in western Kenya (ATSB-Kenya) – Effect of ATSBs on epidemiologic and entomologic indicators: A Phase III, open-label, cluster-randomised, controlled trial
Ogwang, C., Samuels, A. M., McDermott, D. P., Kamau, A., Lesosky, M., Obiet, K., Janssen, J. M., Odongo, W., Gimnig, J. E., Gutman, J. R., Schultz, J. S., Towett, O., Seda, B., Chepkirui, M., Muchoki, M., Omondi, S., Kosgei, J., Polo, B., Aduwo, F. & Otieno, K. & 5 others, , 26 Jun 2025, In: PLOS Global Public Health. 5, 6, e0004230.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus) -
Co-occurrence of native and invasive malaria vectors in anthropogenic habitats in Metehara, Ethiopia: Opportunities for urban malaria control
Ashine, T., Kochora, A., Assefa, M., Negash, N., Gidisa, B., Hailemeskel, E., Alemayehu, M., Assefa, C., Ebabu, M., Mamo Ayana, G., Nigusse, T., Aberra Kassa, F., Esayas, E., Eyasu, A., Chali, S., Epstein, A., Jaiteh, F., Bradley, J., Doumbe-Belisse, P. & Reynolds, A. M. & 5 others, , 24 Nov 2025, In: Current Research in Parasitology and Vector-Borne Diseases. 8, 100337.Research output: Contribution to journal › Article › peer-review
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Does use of domestic insecticides undermine public health control strategies?
Martins, F., Haines, L., Donnelly, M. & Weetman, D., 29 Mar 2025, In: The Lancet Regional Health - Americas. 45, p. 101076 101076.Research output: Contribution to journal › Review article › peer-review
Open AccessFile3 Citations (Scopus) -
Evaluating the impact of two next-generation long-lasting insecticidal nets on malaria incidence in Uganda: an interrupted time-series analysis using routine health facility data
Epstein, A., Gonahasa, S., Namuganga, J. F., Nassali, M. J., Maiteki-Sebuguzi, C., Nabende, I., Snyman, K., Nankabirwa, J. I., Opigo, J., Donnelly, M., Staedke, S., Kamya, M. R. & Dorsey, G., 11 Mar 2025, In: BMJ Global Health. 10, 3, p. :e017106 e017106.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)
Datasets
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Dataset for the article: Attractive Targeted Sugar Baits for malaria control in western Kenya (ATSB-Kenya) – Effect of ATSBs on epidemiologic and entomologic indicators: a Phase III, open-label, cluster-randomised, controlled trial
Ogwang, C. (Creator), Samuels, A. M. (Creator), McDermott, D. (Creator), Kamau, A. (Creator), Lesosky, M. (Creator), Obiet, K. (Creator), Janssen, J. (Creator), Odongo, W. (Creator), Gimnig, J. E. (Creator), Gutman, J. (Creator), Schultz, J. S. (Creator), Towett, O. (Creator), Seda, B. (Creator), Chepkirui, M. (Creator), Muchoki, M. (Creator), Omondi, S. (Creator), Kosgei, J. (Creator), Polo, B. (Creator), Aduwo, F. (Creator), Otieno, K. (Creator), Donnelly, M. (Creator), Kariuki, S. (Creator), Ochomo, E. (Creator), Ter Kuile, F. (Creator) & Staedke, S. (Creator), Liverpool School of Tropical Medicine, 26 Jun 2025
DOI: 10.57978/jzwr-s692
Dataset
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