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Biography

Martin James Donnelly is Professor of Evolutionary Genetics at Liverpool School of Tropical Medicine (LSTM). He is also an Honorary Faculty Member on the Malaria Programme, at the Wellcome Trust Sanger Institute,

Martin trained at Girton College, Cambridge University and LSTM. He then spent two years in the laboratory of Dr Tovi Lehmann at the Centers for Disease Control and Prevention, Atlanta, on an American Society of Microbiology Fellowship, before re-joining LSTM in the Department of Vector Biology in 2001.

Research interests

A major area of interest for Martin is the evolution of insecticide resistance in the malaria mosquito anopheles gambiae. He uses a variety of approaches to identify and validate insecticide resistance associated loci. Much of this work is conducted jointly with Dr David Weetman and team.

A second research area is understanding the impact of insecticide resistance on malaria epidemiology, through observational studies and randomised control trials.

In collaboration with Professor Dominic Kwiatkowski at the Wellcome Sanger Institute, Martin leverages the power of next-generation sequencing technologies to address aspects of the biology of anopheles gambiae that impact the sustainable control of malaria.

With Drs. Eric Ochomo and Ben Abong’o at KEMRI, Kisumu, Martin works on a range of basic and translational science projects including vector control trials and machine learning approaches for identifying insecticide resistant variants in genomic and transcriptomic data sets. With Dr. Luigi Sedda, at Lancaster University (https://www.lancaster.ac.uk/health-and-medicine/about-us/people/luigi-sedda) Martin works on development of spatially explicit sampling frameworks for vectors including adaptive sampling.

With Drs. Catherine Moyes and Penny Hancock from the Big Data Institute, University of Oxford Martin works on geospatial modelling of insecticide resistance.

With Professors Moses Kamya and Sarah Staedke from International Development Research Centre Uganda Martin works on the LLINEUP trial of next generation insecticide treated bednets.

And with Dr Luc Djogbenou based at the Institut Régional de Santé Publique/University of Abomey-Calavi Martin is addresses the interaction between insecticide resistance and vectorial ability in anopheles gambiae.

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