Personal profile
Biography
Research interests
Louise’s research interests are focused on mosquito control and neglected tropical diseases and include insecticide testing, drug discovery and development, and diagnostics. As a Study Director in Liverpool Insect Testing Environment, a client-based facility at LSTM which rears multiple strains of mosquitoes to evaluate the efficacy and durability of mosquito control products, she is interested in research and development of novel insecticide products. Liverpool Insect Testing Environment is a member of the UK Good Laboratory Practice compliance monitoring programme and Louise enjoys working in an environment designed to run studies to these standards. Louise is an author on 40 peer-reviewed publications, 2 book chapters, and 1 patent.
Teaching
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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AWZ1066S, a highly specific anti- drug candidate for a short-course treatment of filariasis.
David Hong, W., Benayoud, F., Nixon, G. L., Ford, L., Johnston, K., Clare, R., Cassidy, A., Cook, D. A. N., Siu, A., Shiotani, M., Webborn, P. J. H., Kavanagh, S., Aljayyoussi, G., Murphy, E., Steven, A., Archer, J., Struever, D., Frohberger, S. J., Ehrens, A. & Hübner, M. P. & 14 others, , 22 Jan 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 4, p. 1414-1419 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile60 Citations (Scopus) -
Wolbachia depletion blocks transmission of lymphatic filariasis by preventing chitinase-dependent parasite exsheathment
Quek, S., Cook, D. A. N., Wu, Y., Marriott, A., Steven, A., Johnston, K., Ford, L., Archer, J., Hemingway, J., Ward, S., Wagstaff, S., Turner, J. & Taylor, M., 12 Apr 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 15, p. e2120003119 e2120003119.Research output: Contribution to journal › Article › peer-review
Open AccessFile19 Citations (Scopus) -
Targeting a microbiota Wolbachian aminoacyl-tRNA synthetase to block its pathogenic host.
Hoffmann, G., Lukarska, M., Clare, R., Masters, E., Johnston, K., Ford, L., Turner, J., Ward, S. A., Taylor, M., Jensen, M. R. & Palencia, A., 10 Jul 2024, In: Science advances. 10, 28, p. eado1453 ado1453.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus) -
Development of Pyrazolopyrimidine Anti-Wolbachia Agents for the Treatment of Filariasis
McGillan, P., Berry, N. G., Nixon, G. L., Leung, S. C., Webborn, P. J. H., Wenlock, M. C., Kavanagh, S., Cassidy, A., Clare, R., Cook, D. A., Johnston, K., Ford, L., Ward, S., Taylor, M., Hong, W. D. & O'Neill, P. M., 9 Sept 2021, In: ACS Medicinal Chemistry Letters. 12, 9, p. 1421-1426 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus) -
Boron-Pleuromutilins as Anti-Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis.
Jacobs, R. T., Lunde, C. S., Freund, Y. R., Hernandez, V., Li, X., Xia, Y., Carter, D. S., Berry, P. W., Halladay, J., Rock, F., Stefanakis, R., Easom, E., Plattner, J. J., Ford, L., Johnston, K., Cook, D. A. N., Clare, R., Cassidy, A., Myhill, L. & Tyrer, H. & 14 others, , 7 Feb 2019, (E-pub ahead of print) In: Journal of Medicinal Chemistry. 62, 5, p. 2521-2540 20 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile38 Citations (Scopus)