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Dr Kayla Barnes

 https://orcid.org/0000-0002-8291-4388

Personal profile

Biography

Kayla Barnes is a genomics researcher based at the Malawi-Liverpool Wellcome Trust. Kayla’s lab focuses on two programs that bookend the dynamics of health in low-income countries. These include tracking viral pathogens and vaccines using wastewater and other surveillance tools and understanding, at the omics cell level, why vaccines underperform in low-income countries. Kayla has helped establish pathogen and single cell sequencing in Malawi.

Research interests

Kayla's research interests include genetics, genomics, immunology, single cell, virology, surveillance, diagnostics, immunity, sequencing, single cell transcriptomics.

Teaching

Kayla offers sequencing and single cell workshops.

Themes

  • Malaria and Neglected Tropical Diseases
  • Innovation to Impact: Therapeutics, Diagnostics, Vaccines

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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Collaborations and top research areas from the last five years

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  • Cost-effectiveness of wastewater-based environmental surveillance for SARS-CoV-2 in Blantyre, Malawi and Kathmandu, Nepal: A model-based study

    Mvundura, M., Ngwira, L. G. C., Shrestha, K. B., Tuladhar, R., Gauld, J., Kerr, C., Barnes, K., Anscombe, C., Sharma, B. & Feasey, N., 24 Apr 2025, In: PLOS Global Public Health. 5, 4 April, p. e0004439 e0004439.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File

  • Maternal-infant rotavirus-specific antibody kinetics to inform timing of vaccine boosting in Malawi: An observational study

    Mandolo, J., Mulira, L., Moyo, M., Mvula, M., Mtonga, F., Henrion, M. Y. R., Wotcheni, W., Cunliffe, N. A., Barnes, K. G., Jambo, K. C. & Jere, K. C., 12 Sept 2025, In: PLoS Medicine. 22, 9, e1004734.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    2 Citations (Scopus)

  • Genome-wide association study identifies human genetic variants associated with fatal outcome from Lassa fever

    Kotliar, D., Raju, S., Tabrizi, S., Odia, I., Goba, A., Momoh, M., Sandi, J. D., Nair, P., Phelan, E., Tariyal, R., Eromon, P. E., Mehta, S., Robles-Sikisaka, R., Siddle, K. J., Stremlau, M., Jalloh, S., Gire, S. K., Winnicki, S., Chak, B. & Schaffner, S. F. & 45 others, Pauthner, M., Karlsson, E. K., Chapin, S. R., Kennedy, S. G., Branco, L. M., Kanneh, L., Vitti, J. J., Broodie, N., Gladden-Young, A., Omoniwa, O., Jiang, P. P., Yozwiak, N., Heuklom, S., Moses, L. M., Akpede, G. O., Asogun, D. A., Rubins, K., Kales, S., Happi, A. N., Iruolagbe, C. O., Dic-Ijiewere, M., Iraoyah, K., Osazuwa, O. O., Okonkwo, A. K., Kunz, S., McCormick, J. B., Khan, S. H., Honko, A. N., Lander, E. S., Oldstone, M. B. A., Hensley, L., Folarin, O. A., Okogbenin, S. A., Günther, S., Ollila, H. M., Tewhey, R., Okokhere, P. O., Schieffelin, J. S., Andersen, K. G., Reilly, S. K., Grant, D. S., Garry, R. F., Barnes, K., Happi, C. T. & Sabeti, P. C., 7 Feb 2024, In: Nature Microbiology. 9, 3, p. 751-762 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    8 Citations (Scopus)

  • Spatially resolved single-cell atlas unveils a distinct cellular signature of fatal lung COVID-19 in a Malawian population

    Nyirenda, J., Hardy, O. M., Silva Filho, J. D., Herder, V., Attipa, C., Ndovi, C., Siwombo, M., Namalima, T. R., Suwedi-Kapesa, L., Ilia, G., Nyasulu, W., Ngulube, T., Nyirenda, D., Mvaya, L., Phiri, J., Chasweka, D., Eneya, C., Makwinja, C., Phiri, C. & Ziwoya, F. & 27 others, Tembo, A., Makwangwala, K., Khoswe, S., Banda, P., Morton, B., Hilton, O., Lawrence, S., dos Reis, M. F., Melo, G. C., de Lacerda, M. V. G., Trindade Maranhão Costa, F., Monteiro, W. M., Ferreira, L. C. D. L., Johnson, C., McGuinness, D., Jambo, K., Haley, M., Kumwenda, B., Palmarini, M., Denno, D. M., Voskuijl, W., Kamiza, S. B., Barnes, K., Couper, K., Marti, M., Otto, T. D. & Moxon, C. A., 20 Nov 2024, (E-pub ahead of print) In: Nature Medicine. 30, 12, p. 3765-3777 13 p., 13850.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    7 Citations (Scopus)

  • Wastewater-based epidemiology as a public health resource in low- and middle-income settings

    Hamilton, K. A., Wade, M. J., Barnes, K., Street, R. A. & Paterson, S., 15 Jun 2024, In: Environmental Pollution. 351, 124045.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    30 Citations (Scopus)
View all 41 research outputs