Personal profile
Research interests
My research focuses on developing and using novel molecular methods for infectious disease surveillance. I am interested in how we can improve and use these techniques to learn more about disease ecology and complex transmission dynamics. I have a particular interest in diseases at the livestock-wildlife-human interface, emerging infectious zoonoses and vector-borne diseases. I am also passionate about building in-country capacity for disease surveillance systems, with a focus on point-of-need molecular diagnostics.
Biography
I am a Research Associate with 8 years of experience in molecular diagnostics and One Health infectious disease research. I lead laboratory-based projects and activities as part of the Tsetse Collective at LSTM, with a focus on trypanosomiasis disease surveillance in tsetse vectors and animal hosts. I develop and use novel molecular tools to learn more about disease ecology, build research capacity and increase accessibility to diagnostics.
I have a background in veterinary medicine, graduating from The Royal Veterinary College with a BSc (Hons) in Veterinary Sciences in 2014. I then went on to complete an MSc in Veterinary Microbiology at the University of Surrey, where I investigated a novel coronavirus species in British hedgehogs in collaboration with Garden Wildlife Health (ZSL) and the Animal and Plant Health Agency. I subsequently worked in a Manchester-based clinical diagnostics start-up, where I developed LAMP assays for the detection of human upper respiratory viral and bacterial pathogens. I joined the Tsetse Collective (led by Prof Steve Torr) as a Research Technician in 2019, becoming a Research Associate and commencing a part-time PhD in 2021.
Outside of work I enjoy trail running, live music and antagonising my cat Ripley.
Teaching
I am a regular contributor to the MSc/MRes courses, where I supervise or co-supervise final research projects, provide practical laboratory training, assist in practical classes (for example, tsetse dissection and FSC field trip) and give lectures on tsetse and other related vectors. I have also run molecular diagnostics training workshops for both Liverpool and field-based staff. In 2024 I qualified as a Fellow of the Higher Education Authority (FHEA).
Themes
- Malaria and Neglected Tropical Diseases
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Research output
- 6 Article
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Caught in a trap: DNA contamination in tsetse xenomonitoring can lead to over-estimates of Trypanosoma brucei infection
Saldanha, I., Lea, R., Manangwa, O., Garrod, G., Haines, L., Acosta-Serrano, A., Auty, H., Betson, M., Lord, J., Morrison, L. J., Mramba, F., Torr, S. & Cunningham, L., 12 Aug 2024, In: PLoS Neglected Tropical Diseases. 18, 8, p. e0012095 e0012095.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus) -
Consistent detection of Trypanosoma brucei but not T. congolense DNA in faeces of experimentally infected cattle
Saldanha, I., Betson, M., Vrettou, C., Paxton, E., Nixon, J., Tennant, P., Ritchie, A., Matthews, K. R., Morrison, L. J., Torr, S. & Cunningham, L., 20 Feb 2024, In: Scientific Reports. 14, 1, p. e4158 4158.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus) -
A pilot study demonstrating the identification of Trypanosoma brucei gambiense and T. b. rhodesiense in vectors using a multiplexed high-resolution melt qPCR
Garrod, G., Adams, E., Lingley, J., Saldanha, I., Torr, S. & Cunningham, L., 25 Nov 2020, In: PLoS Neglected Tropical Diseases. 14, 11, p. 1-12 12 p., e0008308.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus) -
Trypa-NO! contributes to the elimination of gambiense human African trypanosomiasis by combining tsetse control with “screen, diagnose and treat” using innovative tools and strategies
Ndung’u, J. M., Boulangé, A., Picado, A., Mugenyi, A., Mortensen, A., Hope, A., Mollo, B. G., Bucheton, B., Wamboga, C., Waiswa, C., Kaba, D., Matovu, E., Courtin, F., Garrod, G., Gimonneau, G., Bingham, G. V., Hassane, H. M., Tirados, I., Saldanha, I. & Kabore, J. & 26 others, , 12 Nov 2020, (E-pub ahead of print) In: PLoS Neglected Tropical Diseases. 14, 11, p. 1-9 9 p., e0008738.Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Citations (Scopus) -
Extension of the known distribution of a novel clade C betacoronavirus in a wildlife host
Saldanha, I., Lawson, B., Goharriz, H., Rodriguez-Ramos Fernandez, J., John, S. K., Fooks, A. R., Cunningham, A. A., Johnson, N. & Horton, D. L., 3 Apr 2019, In: Epidemiology and Infection. 147, e169.Research output: Contribution to journal › Article › peer-review
Open Access28 Citations (Scopus)